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| トップページ > 研究紹介 >
老化ゲノムバイオマーカー研究チーム
> 老化プロテオーム > 主要文献 |
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老化ゲノムバイオマーカー研究チーム
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1. |
Toda, T., Kaji, K. and Kimura, N. : TMIG-2DPAGE : A new
concept of two-dimensional gel protein database for research
on aging. Electrophoreisis, 19(2), 344-348, 1998 |
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2. |
Toda, T., Satoh, M., Sugimoto, M., Goto, M., Furuichi, Y.
and Kimura, N. : A comparative analysis of the proteins
between the fibroblasts from Werner's syndrome patients and
age-matched normal individuals using two-dimensional gel
electrophoresis.Mech. Ageing Dev., 100(2), 133-143, 1998 |
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3. |
Toda, T.: Two-dimensional electrophoresis database. In
Encyclopedia of Separation Science (Wilson, I. D., Adlard,
T. R., Cooke, M., and Colin F. Poole, C. F., eds.)
pp.2823-2832, Academic Press, New York, 2000 |
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4. |
Toda, T., Sugimoto, M., Omori, A., Matsuzaki, T.,
Furuichi, Y. and Kimura, N.: Proteomic analysis of
Epstein-Barr virus-transformed human B-lymphoblastoid cell
lines before and after immortalization. Electrophoresis,
21(9), 1814-1822, 2000 |
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5. |
Toda, T.: Current status and perspectives of proteomics
in aging research. Exp. Gerontol., 35(6-7), 803-810, 2000 |
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6. |
Toda, T.: Proteome and Proteomics for the research on
protein alterations in aging. New York Acad. Sci., 928,
71-78, 2001 |
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7. |
Nishigaki, R., Shinohara T., Toda, T., Omori, A.,
Ichinose, S., Itoh, M., Shirayoshi, Y.,Kurimasa, A., and
Oshimura, M.: An extra human chromosome 21 reduces mlc-2a
expression in chimeric mice and Down syndrome. Biochem.
Biophys. Res. Comm. 295(1), 112-118, 2002 |
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8. |
Hiratsuka M, Inoue T, Toda T, Kimura N, Shirayoshi Y,
Kamitani H, Watanabe T, Ohama E, Tahimic CG, Kurimasa A,
Oshimura M.: Proteomics-based identification of
differentially expressed genes in human gliomas:
down-regulation of SIRT2 gene. Biochem Biophys Res Commun.
309(3), 558-566, 2003 |
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9. |
Fujinoki, M., Kawamura, T., Toda, T, Ohtake, H., Ishimoda-Takagi,
T., Shimizu, N., Yamaoka,S., Okuno, M.: Identification of
36-kDa flagellar phosphoproteins associated with hamster
sperm motility. J. Biochem. 113, 61-369, 2003 |
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10. |
Takashima M, Kuramitsu Y, Yokoyama Y, Iizuka N, Toda T,
Sakaida I, Okita K, Oka M, Nakamura K.: Proteomic profiling
of heat shock protein 70 family members as biomarkers for
hepatitis C virus-related hepatocellular carcinoma.
Proteomics 3(12), 2487-2493, 2003 |
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11. |
Kamino H, Hiratsuka M, Toda T, Nishigaki R, Osaki M, Ito
H, Inoue T, Oshimura M.: Searching for genes involved in
arteriosclerosis: proteomic analysis of cultured human
umbilical vein endothelial cells undergoing replicative
senescence. Cell Struct Funct. 28(6), 495-503, 2003 |
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12. |
Satouh Y, Padma P, Toda T, Satoh N, Ide H, Inaba K.:
Molecula characterization of radial spoke subcomplex
containing radial spoke protein 3 and heat shock protein 40
in sperm flagella of the ascidian Ciona intestinalis.
Molecular Biology of the Cells, 16, 626-636 (2005). |
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| 13. |
Morisawa H, Toda T.: Collaborative proteomics framework with
XML databases and an integrated XML viewer for 2DPAGE. J
Electrophoresis, 49(1), 35-38 (2005). |
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| 14. |
Saeki K, Yasugi E, Okuma E, Breit SN, Nakamura M, Toda T,
Kaburagi Y, Yuo A.: Proteomic analysis on insulin signaling
in human hematopoietic cells: identification of CLIC1 and
SRp20 as novel downstream effectors of insulin. Am J Physiol
Endocrinol Metab. 289(3), E419-428, 2005. |
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| 15. |
Miura Y, Kano M, Abe K, Urano S, Suzuki S, Toda T.:
Age-dependent variations of cell response to oxidative
stress: proteomic approach to protein expression and
phosphorylation. Electrophoresis. 26(14), 2786-2796, 2005. |
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| 16. |
Sato Y, Yamanaka H, Toda T, Shinohara Y, Endo T.: Comparison
of hippocampal synaptosome proteins in young-adult and aged
rats. Neurosci Lett. 382(1-2), 22-26, 2005. |
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| 17. |
Feng D, Imasawa T, Nagano T, Kikkawa M, Takayanagi K, Ohsawa
T, Akiyama K, Ishigami A, Toda T, Mitarai T, Machida T,
Maruyama N.: Citrullination preferentially proceeds in
glomerular Bowman's capsule and increases in obstructive
nephropathy. Kidney Int. 68(1), 84-95, 2005. |
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| 18. |
Nakamura M, Sakurai Y, Takeda Y, Toda T.: Comparative
proteomics of flotillin-rich Triton X-100-insoluble lipid
raft fractions of mitochondria and synaptosome from mouse
brain. J Electrophoresis. 49(4), 77-83, 2005. |
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| 19. |
Tahimic CG, Tomimatsu N, Nishigaki R, Fukuhara A, Toda T,
Kaibuchi K, Shiota G, Oshimura M, Kurimasa A.: Evidence for
a role of Collapsin response mediator protein-2 in signaling
pathways that regulate the proliferation of non-neuronal
cells. Biochem Biophys Res Commun. 340(4),1244-1250, 2006. |
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| 20. |
Nakamura M, Yamada M, Ohsawa T, Morisawa H, Nishine T,
Nishimura O, Toda T.: Phosphoproteomic profiling of human
SH-SY5Y neuroblastoma cells during response to
6-hydroxydopamine-induced oxidative stress. Biochem Biophys
Acta 1763(9), 977-989, 2006. |
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| 21. |
Morisawa H, Hirota M, Toda T.: Development of an open source
laboratory information management system for 2-D gel
electrophoresis-based proteomics workflow. BMC
Bioinformatics 7:430-440, 2006. |
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| 22. |
Hozumi A, Satouh Y, Makino Y, Toda T, Ide H, Ogawa K, King
SM, Inaba K.: Molecular characterization of Ciona sperm
outer arm dynein reveals multiple components related to
outer arm docking complex protein 2. Cell Motil
Cytoskeleton. 63(10), 591-603, 2006. |
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| 23. |
Sato Y, Suzuki Y, Ito E, Shimazaki S, Ishida M, Yamamoto T,
Yamamoto H, Toda T, Suzuki M, Suzuki A, Endo T.:
Identification and characterization of an increased
glycoprotein in aging: age-associated translocation of
cathepsin D. Mech Ageing Dev. 127(10), 771-778, 2006. |
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| 24. |
Nakahara M, Saeki K, Yogiashi Y, Kimura A, Horiuchi A,
Nakamura N, Yoneda A, Saeki K, Matsuyama S, Nakamura M, Toda
T, Kondo Y, Kaburagi Y, Yuo A.: The protein expression
profile of cynomolgus monkey embryonic stem cells in
two-dimensional gel electrophoresis: a successful
identification of multiple proteins using human databases. J
Electrophoresis 51(1), 1-8, 2007. |
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| 25. |
戸田年総 : 発生・老化研究法 --- 細胞老化 ---. 最新電気泳動実験法(日本電気泳動学会編), pp.
434-438,医歯薬出版, 1999 |
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26. |
戸田年総 : プロテオーム解析とインフォマテックス.二次元電気流動データベース(伊藤隆司/谷口寿章編), pp.
208-216, プロテオミクス, 中山書店, 2000 |
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27. |
戸田年総 : 老化のプロテオーム解析. 遺伝子医学, 4(4), 595-600, 2000 |
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| 28. |
戸田年総 : プロテオームを利用した老化のプロファイリング. 実験医学, 18(18),2490-2496, 2000 |
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| 29. |
戸田年総 : 肺のプロテオーム解析. The Lung Perspectives, 8(3), 294-297,
2000 |
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| 30. |
戸田年総 : プロテオームデータベースの構築と活用. 生物物理化学, 44(3),181-184, 2000 |
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| 31. |
戸田年総 : ゲノム情報とプロテオーム情報の統合によってもたらされる生命情報科学の新展開. 生物物理化学, 45(2),
139-142, 2001 |
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| 32. |
戸田年総 : プロテオーム科学の展望. 日本老年医学雑誌, 39(1), 8-13, 2002 |
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| 33. |
戸田年総 : プロテオームインフォーマティクス ---プロテオームデータベースの構築とその利用---. 医学のあゆみ,
202(5), 319-323, 2002 |
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| 34. |
戸田年総 : 老化のしくみとプロテオミクス ---タンパク質の切り口からみた老化---. 医学のあゆみ, 202(5),
353-357, 2002 |
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| 35. |
蔵満保宏、戸田年総、岡 正朗、沖田 極、中村和行:質量分析計によるタンパク質分子の多様性解析 ---
肝細胞癌グルタミン合成酵素の翻訳後修飾 ---. J. Mass Spectrom. Soc. Jpn., 51(5),
504-508, 2003 |
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| 36. |
戸田年総:リン酸化タンパク質のプロテオーム解析. Molecular Medicine, 41(5), 530-537,
2004 |
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| 37. |
戸田年総:タンパク質の加齢変化. 日本アフェレシス学会雑誌, 23(2), 135-142, 2004 |
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| 38. |
秋山翹一、島田信子、木村成道、戸田年総:
プロテオーム解析におけるリン酸化タンパク質の高感度分析法に関する基礎的検討とミエリン塩基性タンパク質への応用.
生物物理化学, 49(3), 73-81, 2005. |
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| 39. |
戸田年総: CJDと狂牛病に関する分子病理学. 安全医学, 2(2), 31-40,2006. |
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| 40. |
戸田年総: 細胞老化のプロセスを定量的ディファレンシャルプロテオミクスから探る. 分子呼吸器病, 10(2),
82-86, 2006. |
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| 41. |
戸田年総: 疾患プロテオミクス. ファルマシア, 42(1), 2006. |
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| 42. |
戸田年総: 老化のゲノミクスとプロテオミクス. 24(12), 1308-1312, 2006. |
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| 43. |
戸田年総: プロテオーム解析のための最新の質量分析装置. 生物物理化学, 51(1), 1-6, 2007. |
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