財団法人東京都高齢者研究・福祉振興財団　東京都老人総合研究所
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老年病のゲノム解析研究チーム　　

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生活習慣病ゲノム
主要文献

1.

 Shimazoe T, Nakamura S, Kobayashi K, Watanabe S, Miyasaka K , Kono A and Funakoshi A. Role of 5-HT1B receptors in entrainment disorder of Otsuka Long Evans Tokushima Fatty (OLETF) rats. Neuroscience 123: 201-205, 2004.

2.

 Miyasaka K, Yoshida Y, Matsushita S, Higuchi S, Maruyama K, Niino N, Ando F, Shimokata H, Ohta S, Funakoshi A. Association of cholecystokinin-A receptor gene polymorphism with alcohol dependence in a Japanese population. Alcohol and Alcoholism 39: 25-28, 2004.

3.

 Miyasaka K, Yoshida Y, Matsushita S, Higuchi S, Shirakawa O, Shimokata H, Funakoshi A. Association of Cholecystokinin-A Receptor Gene Polymorphisms and Panic Disorder in Japanese Am J Med Genet 127B: 78-80, 2004.

4.

 Suda H, Jimi A, Miyasaka K, Funakoshi A. Histopathological difference between chronic pancreatitis amimal models and human chronic pancreatitis. Pancreas 28: e86-e89, 2004.

5.

 Miyasaka K, Ohta M, Kanai S, Yoshida Y, Sato N, Nagata A, Matsui T, Noda T, Jimi A, Takiguchi S, Takata Y, Kawanami T, Funakoshi A. Enhanced gastric emptying of a liquid gastric load in mice lacking cholecystokinin-B receptor: A study of CCK-A,B, and AB receptor gene knockout mice. J Gastroenterol 39: 319-323, 2004.

6.

 Miyasaka K, Ichikawa M, Momose K, Araki A, Kobayashi M, Ichimaru Y, Funakoshi A. Physiological and pathological age-associated changes in diurnal rhythm of energy expenditure in rats. Arch Geriat Gerontol 39: 83-91, 2004.

7.

 Nomoto S, Ohta M, Kanai S, Yoshida Y, Takiguchi S, Funakoshi A, Miyasaka K. Absence of the cholecystokinin-A receptor deteriorates homeostasis of body temperature in response to changes in ambient temperature. Am J Physiol: Regul Integrative, 287: R556-561,2004.

8.

 Koda M, Ando F, Niino N, Shimokata H, Miyasaka K, Funakoshi A. Association of cholecystokinin 1 receptor and beta3-adrenergic receptor polymorphisms with midlife weight gain. Obes Res 8: 1212-1216, 2004.

9.

 Takano S, Kanai S, Hosoya H, Ohta M, Uematsu H, Miyasaka K. Orexin-A does not stimulated food intake in old rats. Am J Physiol; Gastrointestinal Physiol, 287: G1182-1187, 2004.

10.

 Kitani K, Kanai S, Miyasaka K, Carrilo M-C, Ivy GO. Dose-dependency of life span prolongation of F344/DuCrj rats injected with (-)deprenyl. Biogerontology 6: 1-6, 2005.

11.

 Miyasaka K, Kanai S, Ohta M, Hosoya H. Stimualtory effect of ethanol on pancreatic secretion in conscious rats requires CCK-A receptor. Pancreas 30: e22-28, 2005

12.

 Shimokata, H, Ando F, Niino N, Miyasaka K, Funakoshi A, Cholecystokinin A receptor gene promoter polymorphism and intelligence Ann Epidem 15: 196-201, 2005.

13.

 Miyasaka K, Kawanami T, Shimokata H, Ohta S, Funakoshi A. Inactive aldehyde dehydrogenase-2 increased the risk of pancreatic cancer among smokers in a Japanese male population. Pancreas 30:1-5, 2005.

14.

 Miyasaka K, Hosoya H, Takano S, Ohta M, Sekime A, Kanai S, Matsui T, Funakoshi A. Differences in ethanol ingestion between cholecystokinin-A receptor deficient and -B receptor deficient mice. Alcohol and Alcoholism 40: 176-180, 2005.
　 15. Ishida S, Funakoshi A, Miyasaka K, Iguchi H, Takiguchi S. Sp-family of transcription factors regulates the human SHIP2 gene expression. Gene 348：135-141, 2005.

 　
　 16. Miyasaka K, Ohta M, Takano S, Hayashi H, Higuchi S, Maruyama K, Tando Y, Nakamura T, Funakoshi A. Carboxylester lipase gene polymorphism as a risk of alcohol induced pancreatitis, Pancreas 30: e87-91, 2005 .

 　
　 17. Miyasaka K, Kanai S, Ohta M, Hosoya H, Takano S, Sekime A, Sakurai C, Kaneko T, Tahara S, Funakoshi A. Overeating after restraint stress in cholecystokinin-A receptor deficient mice Jpn J Physiol 55(5):285-291. 2005.

 　
　 18. Akimoto-Takano S, Kanai S, Hosoya H, Ohta M, Uematsu H, Miyasaka K. Differences in the appetite-stimulating effect of orexin, NPY, and ghrelin among young, adult, and old rats. Neuroendocrinology, 82: 256-263, 2005.

 　
　 19. Miyasaka K, Hosoya H, Skime A, Ohta M, Amano H, Matsushita S, Suzuki K, Higuchi S, Funakoshi A. Association of ghrelin receptor gene polymorphism with bulimia nervosa in a Japanese population. J Neural Trasnmission 113: 1279-1285, 2006.

 　
　 20. Ishida S , Funakoshi A, Miyasaka K, Shimokata H, Ando F, Takiguchi S. Association of SH-2 containing inositol 5'-phosphatase 2 (SHIP2) gene polymorphisms and impaired glucose tolerance. Pancreas 33: 63-67, 2006.

 　
21. Miyasaka K, Nomoto S, Ohta M, Kanai S, Kaneko T, Tahara S, Funakoshi A. Disturbance of response to acute thermal pain in naturally occurring cholecysotkinin-A receptor gene knockout Otsuka Long-Evans Tokushima Fatty (OLETF) rats. J Pharmacol Sci 101: 280-285, 2006.
22. Hayashi H, Kanai s, Yamada Y, Tsushima M, Miyasaka K. Acute inhibition of lymphatic cholesterol transport in rat intestine by SCH 58053 J Atheroscler Thromb 13: 240-246, 2006.
23. Sakurai C, Ohta M, Kanai S, Uematsu H, Funakoshi A, Miyasaka K. Lack of ghrelin secretion in response to fasting in cholecystokinin-A (-1), -B (-2) receptor-deficient mice. J Physil Sci 56: 441-447, 2006.
24. Kanai S, Hiroko Hosoya H, Minoru Ohta M, Miyasaka K. Decreased H+,K+-ATPase expression and gastric acid secretory
capacity in aged mice. Arch Geriat Gerontol in press
25. Miyasaka K, Kanai S, Ohta M, Hosoya H, Sekime A, Akimoto S, Takiguchi S, Funakoshi A. Age-associated gallstone formation in male and female CCK-1(A) receptor deficient mice. J Gastroenterol in press

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財団法人東京都高齢者研究・福祉振興財団東京都老人総合研究所、トップページへ
2007/05/23
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