独立行政法人 東京都健康長寿医療センター 研究所(東京都老人総合研究所)
 トップページ > 研究紹介 > 老化制御研究チーム > 分子老化制御研究 > 主要文献

老化制御研究チーム 

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分子老化制御研究

主要文献
1.  Amano, A., Handa, S., Aigaki, T., Shigemoto, K., Maruyama, N. Ishigami, A.: Establishment and characterization of hepatocytes from an Immortomouse / SMP30/GNL knockout mouse hybrid lacking vitamin C to study vitamin C transport. J Biochem (2011) (in press)

2.  Kondo, Y., Higashi, C., Iwama, M., Ishihara, K., Handa, S., Mugita, H., Maruyama, N., Koga, H., Ishigami, A.: Bioavailability of vitamin C from mashed potatoes and potato chips after oral administration in healthy Japanese men. Br J Nutr (2011) (in press)

3.  Coudane, F., Mechin, M.C., Huchenq, A., Henry, J., Nachat, R., Ishigami, A., Adoue, V., Sebbag, M., Serre, G., Simon, M.: Deimination and expression of peptidylarginine deiminases during cutaneous wound healing in mice. Eur J Dermatol 21: 376-384 (2011)

4.  Hotta, H., Uchida, S., Kagitani, F., Maruyama, N.: Control of cerebral cortical blood flow by stimulation of basal forebrain cholinergic areas in mice. J Physiol Sci 61: 201-209 (2011)

5.  Ishii, T., Miyazawa, M., Onodera, A., Yasuda, K., Kawabe, N., Kirinashizawa, M., Yoshimura, S., Maruyama, N., Hartman, P.S., Ishii, N.: Mitochondrial reactive oxygen species generation by the SDHC V69E mutation causes low birth weight and neonatal growth retardation. Mitochondrion 11: 155-165 (2011)

6.  Iwama, M., Shimokado, K., Maruyama, N., Ishigami, A.: Time course of vitamin C distribution and absorption after oral administration in SMP30/GNL knockout mice. Nutrition 27: 471-478 (2011)

7.  Jang, B., Shin, H.Y., Choi, J.K., Nguyen du, P.T., Jeong, B.H., Ishigami, A., Maruyama, N., Carp, R.I., Kim, Y.S., Choi, E.K.: Subcellular localization of peptidylarginine deiminase 2 and citrullinated proteins in brains of scrapie-infected mice: nuclear localization of PAD2 and membrane fraction-enriched citrullinated proteins. J Neuropathol Exp Neurol 70: 116-124 (2011)

8.  Amano, A., Aigaki, T., Maruyama, N., Ishigami, A.: Ascorbic acid depletion enhances expression of the sodium-dependent vitamin C transporters, SVCT1 and SVCT2, and uptake of ascorbic acid in livers of SMP30/GNL knockout mice. Arch Biochem Biophys 496: 38-44 (2010)

9.  Hasegawa, G., Yamasaki, M., Kadono, M., Tanaka, M., Asano, M., Senmaru, T., Kondo, Y., Fukui, M., Obayashi, H., Maruyama, N., Nakamura, N., Ishigami, A.: Senescence marker protein-30/gluconolactonase deletion worsens glucose tolerance through impairment of acute insulin secretion. Endocrinology 151: 529-536 (2010)

  10.  Ishigami, A., Maruyama, N.: Importance of research on peptidylarginine deiminase and citrullinated proteins in age-related disease. Geriatrics & Gerontology International 10: S53-S58 (2010)
 
 
  11.  Jang, B., Jin, J.K., Jeon, Y.C., Cho, H.J., Ishigami, A., Choi, K.C., Carp, R.I., Maruyama, N., Kim, Y.S., Choi, E.K.: Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease. Acta Neuropathol 119: 199-210 (2010)

 
  12.  Koike, K., Kondo, Y., Sekiya, M., Sato, Y., Tobino, K., Iwakami, S.I., Goto, S., Takahashi, K., Maruyama, N., Seyama, K., Ishigami, A.: Complete lack of vitamin C intake generates pulmonary emphysema in senescence marker protein-30 knockout mice. Am J Physiol Lung Cell Mol Physiol 298: L784-792 (2010)

 
  13.  Maruyama, N., Ishigami, A., Kondo, Y.: Pathophysiological significance of senescence marker protein-30. Geriatrics & Gerontology International 10: S88-S98 (2010)

 
  14.  Ogiwara, Y., Mori, S., Iwama, M., Sawabe, M., Takemoto, M., Kanazawa, N., Furuta, K., Fukuda, I., Kondo, Y., Kimbara, Y., Tamura, Y., Chiba, Y., Araki, A., Yokote, K., Maruyama, N., Ito, H.: Hypoglycemia due to ectopic secretion of insulin-like growth factor-I in a patient with an isolated sarcoidosis of the spleen. Endocr J 57: 325-330 (2010)

 
  15.  Park, H., Ishigami, A., Shima, T., Mizuno, M., Maruyama, N., Yamaguchi, K., Mitsuyoshi, H., Minami, M., Yasui, K., Itoh, Y., Yoshikawa, T., Fukui, M., Hasegawa, G., Nakamura, N., Ohta, M., Obayashi, H., Okanoue, T.: Hepatic senescence marker protein-30 is involved in the progression of nonalcoholic fatty liver disease. J Gastroenterol 45: 426-434 (2010)
 
 
  16.  Park, J.K., Hong, I.H., Ki, M.R., Chung, H.Y., Ishigami, A., Ji, A.R., Goo, M.J., Kim, D.H., Kwak, J.H., Min, C.W., Lee, S.S., Jeong, K.S.: Vitamin C deficiency increases the binucleation of hepatocytes in SMP30 knock-out mice. J Gastroenterol Hepatol 25: 1769-1776 (2010)
 
 
  17.  Park, J.K., Ki, M.R., Lee, H.R., Hong, I.H., Ji, A.R., Ishigami, A., Park, S.I., Kim, J.M., Chung, H.Y., Yoo, S.E., Jeong, K.S.: Vitamin C deficiency attenuates liver fibrosis by way of up-regulated peroxisome proliferator-activated receptor-gamma expression in senescence marker protein 30 knockout mice. Hepatology 51: 1766-1777 (2010)
 
 
  18.  Sato, Y., Uchiki, T., Iwama, M., Kishimoto, Y., Takahashi, R., Ishigami, A.: Determination of dehydroascorbic acid in mouse tissues and plasma by using tris(2-carboxyethyl)phosphine hydrochloride as reductant in metaphosphoric acid/ethylenediaminetetraacetic acid solution. Biol Pharm Bull 33: 364-369 (2010)
 
 
  19.  Shimada, N., Handa, S., Uchida, Y., Fukuda, M., Maruyama, N., Asaga, H., Choi, E.K., Lee, J., Ishigami, A.: Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain. J Neurosci Res 88: 798-806 (2010)
 
 

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独立行政法人 東京都健康長寿医療センター 研究所(東京都老人総合研究所)、トップページへ
2011/11/04
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