運動器医学研究-主要文献

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老年病研究チーム　

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運動器医学研究

Mori,S., Kishi, M., Kubo,S., Akiyoshi,T., Yamada,S., Miyazaki, T., Konishi,T., Maruyama,N., and Shigemoto, K. 2012. 3,4-diaminopyridine improves neuromuscular transmission in a MuSK antibodies-induced mouse model of myasthenia gravis. J Neuroimmunol in press.

Mori,S., Yamada,S., Kubo,S., Chen,J., Matsuda,S., Shudou,M., Maruyama,N., and Shigemoto, K. 2012. Divalent and monovalent autoantibodies cause dysfunction of MuSK by distinct mechanisms in a rabbit model of myasthenia gravis. J Neuroimmunol in press.
　

Mori,S., Kubo,S., Akiyoshi,T., Yamada,S., Miyazaki, T., Hotta,H., Desaki,J., Kishi, M., Konishi,T., Nishino,Y., Miyazawa, A., Maruyama,N., and Shigemoto, K. 2012. Antibodies against Muscle-Specific Kinase Impair Both Presynaptic and Postsynaptic Functions in a Murine Model of Myasthenia Gravis. Am J Pathol 180:798-810.
　

Muraoka, T., Aoki, K., Iwasaki, T., Shinoda, K., Nakamura, A., Aburatani, H., Mori, S., Tokuyama, K., Kubota, N., Kadowaki, T., et al. 2011. Ezetimibe decreases SREBP-1c expression in liver and reverses hepatic insulin resistance in mice fed a high-fat diet. Metabolism 60:617-628.

Shigemoto, K., Kubo, S., Mori, S., Yamada, S., Akiyoshi, T., and Miyazaki, T. 2010. Muscle weakness and neuromuscular junctions in aging and disease. Geriatr Gerontol Int 10 Suppl 1:S137-147.

Iwasawa, M., Miyazaki, T., Nagase, Y., Akiyama, T., Kadono, Y., Nakamura, M., Oshima, Y., Yasui, T., Matsumoto, T., Nakamura, T., et al. 2009. The antiapoptotic protein Bcl-xL negatively regulates the bone-resorbing activity of osteoclasts in mice. J Clin Invest 119:3149-3159.

Shigemoto, K., Kubo, S., Jie, C., Hato, N., Abe, Y., Ueda, N., Kobayashi, N., Kameda, K., Mominoki, K., Miyazawa, A., et al. 2008. Myasthenia gravis experimentally induced with muscle-specific kinase. Ann N Y Acad Sci 1132:93-98.

Konishi, T., Ohta, K., Shigemoto, K., and Ohta, M. 2007. Anti-alkaline phosphatase antibody positive myasthenia gravis. J Neurol Sci 263:89-93.

Ohta, K., Shigemoto, K., Fujinami, A., Maruyama, N., Konishi, T., and Ohta, M. 2007. Clinical and experimental features of MuSK antibody positive MG in Japan. Eur J Neurol 14:1029-1034.

10.

Mori, S., and Tokuyama, K. 2007. Variation in ACE activity affects myogenic differentiation in C2C12 cells. Biochem Biophys Res Commun 353:369-375.

11.

Mori, S., and Tokuyama, K. 2007. ACE activity affects myogenic differentiation via mTOR signaling. Biochem Biophys Res Commun 363:597-602.

12.

Abe, Y., Takeuchi, T., Kagawa-Miki, L., Ueda, N., Shigemoto, K., Yasukawa, M., and Kito, K. 2007. A mitotic kinase TOPK enhances Cdk1/cyclin B1-dependent phosphorylation of PRC1 and promotes cytokinesis. J Mol Biol 370:231-245.

13.

Shigemoto, K., Kubo, S., Maruyama, N., Hato, N., Yamada, H., Jie, C., Kobayashi, N., Mominoki, K., Abe, Y., Ueda, N., et al. 2006. Induction of myasthenia by immunization against muscle-specific kinase. J Clin Invest 116:1016-1024.
　

14.

Miyazaki, T., Tanaka, S., Sanjay, A., and Baron, R. 2006. The role of c-Src kinase in the regulation of osteoclast function. Mod Rheumatol 16:68-74.

15.

Ohta, K., Shigemoto, K., Kubo, S., Maruyama, N., Abe, Y., Ueda, N., Fujinami, A., and Ohta, M. 2005. MuSK Ab described in seropositive MG sera found to be Ab to alkaline phosphatase. Neurology 65:1988.

16.

Manktelow, E., Shigemoto, K., and Brierley, I. 2005. Characterization of the frameshift signal of Edr, a mammalian example of programmed -1 ribosomal frameshifting. Nucleic Acids Res 33:1553-1563.

17.

Ohta, K., Shigemoto, K., Kubo, S., Maruyama, N., Abe, Y., Ueda, N., and Ohta, M. 2004. MuSK antibodies in AChR Ab-seropositive MG vs AChR Ab-seronegative MG. Neurology 62:2132-2133.

18.

Shigemoto, K., Brennan, J., Walls, E., Watson, C.J., Stott, D., Rigby, P.W., and Reith, A.D. 2001. Identification and characterisation of a developmentally regulated mammalian gene that utilises -1 programmed ribosomal frameshifting. Nucleic Acids Res 29:4079-4088.
　

19.

Shigemoto, K., Kubo, S., Maruyama, N., Yamada, S., Obata, K., Kikuchi, K., and Kondo, I. 2000. Identification and characterization of 5' extension of mammalian agrin cDNA, the exons and the promoter sequences. Biochim Biophys Acta 1494:170-174.
　